Alaska INBRE awards $650,000 for One Health research grants

November 7, 2019

Jeff Richardson

The University of Alaska Fairbanks has awarded nearly $650,000 in Institutional Development Awards to fund eight pilot research projects. Through the IDeA Networks of Biomedical Research Excellence, or INBRE, the funding will support studies on a diverse range of topics that include salmon migration, tick-borne pathogens and the use of pesticides in Alaska lakes.

The awards represent the first round of funding from a five-year, $19.6 million National Institutes of Health grant, which UAF received in August to build capacity and increase diversity of students among its statewide network in biomedical research.

The NIH grant is being used to build interdisciplinary collaborations following a One Health approach, which investigates the health of people, animals and their shared environment in Alaska.

Awardees include eight researchers from UAF and the University of Alaska Anchorage:

• Kristen Gorman, a research ecologist for UAF’s College of Fisheries and Ocean Sciences, will receive $98,615 for her project “Effects of energetic state and infectious agents on migration by sockeye salmon.” Research will explore whether Alaska salmon can be resilient to infectious agents amid significant environmental changes.

• Micah Hahn, an assistant professor of environmental health for UAA, was awarded $99,994 for “Understanding the risk of ticks and tick-borne pathogens in Alaska.” The ongoing study, which is entering its second year, has a goal of identifying and monitoring ticks in Alaska, and to enhance detection of pathogens they may carry.

• Kristin O’Brien, a professor of biology at UAF, will use $74,874 to study “Effects of polyglutamine and glutamic acid repeats on HIF-1 function.” The goal of the study is to determine the capacity of polar fishes to withstand changing conditions, particularly in oxygen deficient environments.

• S. Ryan Oliver, an assistant professor of chemistry at UAF, was awarded $75,000 for “Skeletal muscle thermogenesis by sarcolipin-uncoupling in ground squirrels.” The study will work to expand our current understanding of thermoregulation in hibernating animals, which could eventually translate into future medical treatments.

• Patrick Tomco, an assistant professor of chemistry at UAA, will receive $100,000 to study “Cold-region environmental behavior of rotenone and applications to exposure prevention.” His research will focus on how rotenone, a pesticide used to control Northern pike populations, degrades in cold and dark climates.

• Maegan Weltzin, an assistant professor of chemistry at UAF, was awarded $75,000 for “Pharmacology and function of nicotinic receptors altered by an epilepsy mutation.” The study aims to improve our understanding of the cellular mechanisms underlying epilepsy.

• Cory Williams, an assistant professor of biology at UAF, will receive $50,000 to study “Effects of photoperiod and dopamine disruption on sleep and mass gain.” The study will examine how daylight and diet influence several factors that may play a role in seasonal affective disorder.

• Matthew Wooller, a professor at UAF’s Institute of Northern Engineering, was awarded $75,000 for “Dried blood spots as a tool for diet and trace element exposure assessment.” The research will work to validate a method to assess diet and trace element exposure levels from dried blood spots.